Friday, April 05, 2002 6:09 PM Subject: Karla > 4/4/02 > > Results of Karla's first visit with the medical-oncologist, Dr. FaiChe > Lee@ UNM Cancer Center > > > Dr. Lee confirms diagnosis of inflammatory breast cancer and recommends > aggressive chemotherapy with a total of 8 rounds consisting of 4 rounds > of Adriamycin/Cytoxan combination followed immediately by 4 rounds of > Taxol or Taxotier. This is neo-adjuvant therapy meaning chemo before > surgery. Results of most recent studies show this combo most effective > in reducing tumor size or eliminating tumor prior to surgical > intervention in the form of lumpectomy or mastectomy. Dr. Lee says that > 14-15% of women receiving this particular therapy have no evidence of > tumor after the chemotherapy. He says further that 2/3 of the women who > had planned mastectomy following chemo were able to have a lumpectomy > instead. The chemo will be delivered every three weeks in the Infusion > suites at the Cancer Center, intravenously through a Porta-Cath. This is > a central line catheter which will be placed under the skin in her upper > chest. It is an out-patient procedure done with local anesthesia. It > will be nearly invisible, and allow the chemo needle to be placed each > time with relative ease and minimal discomfort for Karla. > > So-the plan now is for 8 rounds of chemo (3 weeks apart), then surgery > (either lumpectomy or mastectomy, to be determined by her response to > the chemo) followed by radiation therapy. Dr. Lee said this will all be > completed after close to a years time. > > The good news is her labs came back estrogen receptor positive and the > bad news is the HRTII was positive. Not sure of the implications of > either of these but for those of you who are oncologists, it may mean > something. The surgeon said on Wednesday that the cancer is a Stage III. > > He will treat her concurrently with tamoxifen, an oral hormone therapy > that he feels will add to the aggressiveness of the treatment. > > The chemo can cause fatigue due in part to anemia from bone marrow > suppression. White blood cells can decrease, making her less able to > fight off infection, and her platelet levels can decrease (platelets > help the blood to clot) She will loose her hair after the second round > of chemo. He says typically the week after, a person will feel tired; > the second week the bone marrow is suppressed and the third week the > bone marrow recovers. Nausea can also occur after chemo. He gave her > medication for this. He said he would, if needed, use a medication > called Procrit if she needed it to fight the anemia, which might also > help with fatigue. The good news, he says, is that Karla is in > excellent physical shape, and the fact that she is a runner and a cycler > will only add to the bodies ability to respond to the chemo and add to > her bodies ability to fight infection, to offset the negative symptoms > of chemo, and have a positive impact on survival. He recommends a good > diet and continued exercise throughout, as she is able. He says some > women aren't even bothered too much by the chemo! He agrees to her using > herbal medicine and is open minded about the use of complimentary > therapy. > > Dr. Lee wasn't able to give us information on the possibility of cure. > He says everyone responds differently and we just have to take it a step > at a time. He has ordered a bone scan to determine if it has spread to > the bone. If there is bone metastases, the goal will be palliative, and > if not the goal will be curative. He says whether the goal is palliative > or curative, we will do chemo either way. He did say there was lymph > node involvement. > > There is lots of info on the internet on INFLAMMATORY BREAST CANCER. I > did a "search" through MSN. It will be a difficult year, but CURE is > possible! The positive mind-body connection that is so strong in Karla, > modern medicine, and the collective love, prayers , positive energy and > support of so many that love her will only add to the CURE potential. > > SHE WILL BE AMONG THE PERCENTAGE OF WOMEN WHO ARE CURED!!! > > > Her schedule thus far: > > Tues 4/9 2:00 : Teaching session for Porta-Cath self care and > chemo > > Fri 4/12 10:00: Porta-Cath placement > To follow: Ist Chemo > > Wed 4/17 8:00: Bone Scan > > Mon 5/6 9:30: 2nd Chemo > > > Karla will have subsequent chemo treatments on Mondays every 3 weeks > > > -Kris Coughenour > >